Trial Number
593-25
Condition
Stroke
Participant Age Range
18 to 90 years old
Participant Gender
Any
Enrolling Participants
Yes
Overview
“A Phase II, Randomized, Placebo-Controlled, Double-Blind, Adaptive Study to Assess the Safety and Efficacy of Intravenous J147 Combined with Endovascular Therapy in Patients with Acute Ischemic Stroke”
Researchers are studying whether an investigational medication called J147 can improve outcomes for people experiencing an acute ischemic stroke. Participants who undergo standard clot-removal treatment (endovascular thrombectomy), with or without clot-dissolving medication, will receive either J147 or a placebo. The study will evaluate the safety of J147 and whether it may help reduce brain injury, inflammation, and disability after stroke.