About
Matthew Gandjian, MD, is a cardiac and aortic surgeon dedicated to providing thoughtful, evidence-based surgical care with an emphasis on technical excellence, sound clinical judgment, and individualized treatment.
Dr. Gandjian earned his medical degree from the University of Miami Miller School of Medicine and completed his general surgery residency at Harbor-UCLA Medical Center, where he served as administrative chief resident. He subsequently completed fellowship training in cardiothoracic surgery at UCLA Health. His clinical interests include coronary artery bypass surgery, surgical treatment of valvular heart disease, complex aortic surgery, and minimally invasive procedures for atrial fibrillation. His academic work focuses on improving surgical outcomes and advancing the quality of care delivered to cardiac surgery patients, and he has authored numerous publications in leading peer-reviewed medical journals.
Dr. Gandjian was drawn to cardiac surgery for its unique combination of complex decision-making, technical precision, and the opportunity to make a lasting difference in patients' lives. He believes excellent surgical care extends beyond the operating room and is built on careful listening, honest communication, and a strong physician-patient relationship. He strives to ensure that each patient feels informed, supported, and confident throughout every stage of their care.
A native of Los Angeles, Dr. Gandjian speaks fluent Farsi and Spanish. Outside of medicine, he enjoys spending time with family and friends, exploring new restaurants, cooking, staying active, and playing tennis.
Languages
English, Farsi, Spanish
Provider Specialty
Cardiothoracic - Thoracic Surgery, Surgery - Cardiothoracic
Education
Medical School
University of Miami - Miller School of Medicine
2016
Residency Program - Anesthesiology
Harbor / UCLA Medical Center
2017
Residency Program - Cardiothoracic Surgery
UCLA Medical Center
2026
Locations & Affiliations
Locations
MemorialCare Cardiothoracic Surgery - Saddleback Medical Center (Medical Office Tower)
24411 Health Center Drive
Suite 520
Laguna Hills, CA
Office: 949-268-4568
Insurance
Please consult your health care provider or health plan for the most accurate information about your health plan’s coverage of a particular health care service offered at a MemorialCare facility. Learn more about our Accepted Health Plans.