The major soft tissue sarcomas encountered in children, adolescents, and young adults account for 7 % of cancer in this age group. These tumors include a rhabdomyosarcoma (RMS), a non-rhabdomyosarcoma soft tissue sarcoma (NRSTS), or another type of soft tissue tumor. A goal of this study is to collect soft tissue sarcoma specimens to learn more about RMS and NRSTS, and the blood, serum and bone marrow of people with these tumors. Additionally, we would like to bank these samples for future research. Research performed on these samples may include such things as DNA testing to identify changes in the genetic information causing the tumor and what might explain why treatment drugs work or do not work. These aims will ultimately help researchers understand the biological mechanisms of these tumors and aide in the treatment plans for these patients.