Asthma and Infectious Triggers

Service: Trial Number:
015-11
Principal Investigator: Conducted at:
Miller Children`s & Women`s Hospital Long Beach
Currently enrolling additional patients:
Yes
Age Range:
All ages

Asthmatic patients are often started on antibiotics prior to admission to the hospital for an asthmatic attack. Other times antibiotics are started after admission to the Pediatric Intensive Care Unit . Often they are started without clear evidence of infection. Although there is no evidence that antibiotics improve outcomes for asthma exacerbations without infection, it still appears to be a common practice to prescribe them. The objective of this study is to try to determine what proportion of asthmatics admitted to a PICU have evidence of infection (either viral or bacterial) and how often antibiotics are given as part of the treatment regimen. Clinical data will be collected and all antibiotics will be recorded in this retrospective chart review of patients with admission to the hospital with a diagnosis of asthma or status asthmaticus between July 2008 and July 2011. All patients from age 6 months to 21 years will be included. Patients that have reactive airway disease, bronchiolitis, and bronchopulmonary dysplasia without the clear diagnosis of asthma will be excluded. Patients of all ethnic backgrounds will be included. Sputum cultures and chest radiographs will be recorded. A diagnosis of pneumonia will be sought and correlated with the antibiotic treatment.