ACCL0934: A Randomized Trial of Levofloxacin to Prevent Bacteremia in Children Being Treated for Acute Leukemia (AL) or Undergoing Hematopoietic Stem Cell Transplantation (HSCT)

Service: Trial Number:
Principal Investigator: Conducted at:
Miller Children's & Women's Hospital Long Beach
Currently enrolling additional patients:
Age Range:
Ages ≥ 6 months to ≤21 years
Male & Female

When patients receive intensive cancer treatment for acute leukemia or a stem cell transplant, bacterial infections can develop which can make you very sick. This study looks at how well treatment with an antibiotic, called levofloxacin, can prevent bacterial infection from developing in children and young adults receiving intensive cancer treatment or a stem cell transplant. The levofloxacin treatment to prevent bacterial infection is experimental. The overall goal of this study is to compare the effects, good and/or bad, of levofloxacin on people receiving intensive cancer treatment or stem cell transplant to find out if it is better than no preventive bacterial infection treatment.