Trial Number

015-20

Condition

Stroke

Participant Age Range

18 years and younger

Participant Gender

Any

Enrolling Participants

Yes

Overview

Anticoagulation in Intracerebral Hemorrhage (ICH) Survivors for Stroke Prevention and Recovery

A substantial portion of intracerebral hemorrhage (ICH) survivors have atrial fibrillation/flutter (AF) and are at high risk for subsequent ischemic stroke. Although randomized clinical trials have established theeffectiveness of anticoagulant therapy for preventing ischemic stroke in patients with AF, these trials did not enroll ICH patients because of concern that a potential increase in risk for recurrent hemorrhagic strokes would offset any benefit. The Anticoagulation in Intracerebral Hemorrhage Survivors for Stroke Prevention and Recovery (ASPIRE) study is a randomized, double-blinded, phase III clinical trial designed to test the efficacy and safety of anticoagulation, compared with aspirin, in patients with a recent ICH and high-risk nonvalvular AF.

Provider

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