Trial Number


Age range

18 years and older


Male or Female

Enrolling Patients


RELIEVE-HF is a global, 500 patient pivotal study of its proprietary, minimally invasive implanted interatrial shunt device for treating patients with NHYA Class III and ambulatory Class IV symptomatic heart failure (HF). This randomized, controlled, double-blinded multicenter clinical trial – the RELIEVE-HF study – will evaluate the safety and effectiveness of V-Wave’s novel device therapy in severe HF patients with either preserved or reduced ejection fraction.

Principal Investigator

MemorialCare Research Center Contact Form

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